Publications


Prof. Lukshmy Menik Hettihewa


Full Articles


• Liu Z1, Hettihewa M2, Shu Y1, Zhou C1, Wan Q1, Liu L3. The mechanism of the adsorption of dsDNA on citrate-stabilized gold nanoparticles and a colorimetric and visual method for detecting the V600E point mutation of the BRAF gene. 2018 Mikrochim Acta. 2018 Mar 27;185(4):240. doi: 10.1007/s00604-018-2775-9.

• Hettihewa menik , Vajira Buliugahapitiya, Amila Miunasinghe, Nubuhiro Kihara. Cytotoxic Assay and Human Telomerase Reverse Transcriptase Assay of Flueggea leucopyrus Wild. on Human Ovarian Carcinoma Cells Conference Paper 13th Academic Session, University of Ruhuna, Sri Lanka march 2016 Volume: 13

• Hettihewa menik , Vajira Buliugahapitiya, Amila Miunasinghe, Nubuhiro Kihara. Evaluation of Anti-Oxidant Power of Flueggea leucopyrus. Willd, a Medicinal Herb Used as Complementary Medicine for Cancer and Characterization of New Anti-Cancer Compounds conference paper Feburary 2016, 18th International Conference on Natural Products and Drug Discovery. Qualar Lampur, Malaysia

• L.M. Hettihewa, M.M.A.B. Munasinghe, Vajira P. Bulugahapitiya, Nobuhiro Kihara. Dose dependent anti proliferative and cytotoxic effects of flueggea leucopyrus willd against human ovarian carcinoma; mts and human telomerase enzyme inhibition European Journal of Biomedical AND Pharmaceutical sciences 2015; 2:7 14-18

• Subasinghe HWAS, Hettihewa LM, GunawardenaS, Liyanage T. Evaluation Of Aqueous Extract Of Costus Speciosus (J.König)Sm. Leaf For Hepatic And Renal Toxicities: Biochemical And Histopathological Perspectives ejpmr, 2015,2(4), 01- 12

• Hettihewa LM, Sirisena B. Causality assessment and the severity of the adverse drug reactions (ADR) actively detected in hospital in patients in tertiary care hospital Sri Lanka: prospective observational survey. Asian Journal of Research in Biological and Pharmaceutical Sciences. 2(1), 2014, 1 – 10.9

• Vajira P. Bulugahapitiya, Amila Bandara Munasinghe and Menik Hettihewa. Investigation of chemical composition of flueggea leucopyrus (willd.) World journal of pharmacy and pharmaceutical sciences, 2014; 3:8;79-94. ISSN 2278 – 4357

• Sandhya VG. Nair, Menik Hettihewa and H. P. Vasantha Rupasinghe. Apoptotic and Inhibitory Effects on Cell Proliferation of Hepatocellular Carcinoma HepG2 Cells by Methanol Leaf Extract of Costus speciosus. Biomed Research International, Volume 2014, Article ID 637098, 10 pages.http://dx.doi.org/10.1155/2014/637098

• Subasinghe HWAS, Hettihewa LM ,Gunawardana S, Liyanage T. Methanol and water extracts of costus speciosus (J KONIG) leaves reverses the high fat diet induced peripheral insulin resistance in experimental wistar rats. Int. res. J. Pharm 2014;5(2)

• Knowledge of Sri Lankan government medical practitioners and medical students on standard treatment guidelines; regional cross sectional survey 2013 IJNPD 3;2
108-113.http://www.ijnpnd.com/article.asp?issn=2231- 0738;year=2013;volume=3;issue=2;spage=108;epage=113;aulast=Hettihewa;type=0

• Hettihewa LM. Tharanga Dadallage and Inoka Wimalasena. Core knowledge in key policies in drug formulary and interventions for prescribing practice among medical officers and students;Sri Lanka perspective. Int. res. J. Pharm 2013;4(12)

• Hettihewa LM Prospective analysis of actively screened adverse drug reaction profile presented into the inward set up in government tertiary hospital in Sri Lanka. Clin Exp Pharmacol 2012, 2:3. http://dx.doi.org/10.4172/2161- 1459.S1.003

• Hettihewa LM, Wimalasena I Dadallage T. Cost – utility analysis of parenteral antibiotics prescribed in medical wards in a tertiary care health facility in southern province of Sri Lanka OJHAS 11 ;3 july sept 2012 10

• Hettihewa LM percepts and practices in drug use indicators at government health care facilities; hospital based prospective analysis. IJP 2011 43; 1 91-2. It is indexed in science citation index.
http://medind.nic.in/ibi/t11/i1/ibit11i1p89.pdf

• Hettihewa LM prolong expression of MHC class I peptide expression in bone marrow derived retrovirus transfected matured dendritic cells by continuous centrifugation in the presence of IL 4. IJMR . Indian J Med Res v.134(5); Nov 2011 International journal of medical research is an official publication of Indian Journal of medical research and indexed in Science citation index as well.
http://icmr.nic.in/ijmr/2011/november/1113.pdf

• Hettihewa LM, Effects of HCT on K dependent pancreatic response and the correlation with blood sugar insulin in patients with essential hypertension IJNPND 2011 1;1 73-77. http://www.ijnpnd.com/article.asp?issn=2231-0738;year=2011;volume=1;issue=1;spage=73;epage=77;aulast=Hettihewa

• Hettihewa LM and Weerarathna TP. Comparison of McAuley/fasting insulin indices with ATP III clinical criteria for the diagnosis of insulin resistance in type 2 diabetes mellitus. 2011J Pharmacol Pharmacother. 2011 Jul-Sep; 2(3): 165–69. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157124/

• Hettihewa LM. Amrasinghe ATIM, Jayarathna KAKT. Prospective encounter study the degree of adherence to patient care indicators in Health Care facilities; Sri Lankan perspective. J pharm Bioall Sci v.3(2); Apr-Jun 2011 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103928/

• Hettihewa LM, Jayarathna KAKT Comparison of the Knowledge in Core Policies of Essential Drug List Among Medical Practitioners and Medical Students in Galle, Sri Lanka OJHAS Vol. 9, Issue 3: (Jul – Sep, 2010). This journal is indexed and peer review journal published more than two issues per year.
http://www.ojhas.org/issue35/2010-3-7.html11

• Hettihewa L Menik, Amrasinghe I.Isuru, Subasinghe Sewwandi Survey ; Precepts and Practices in Drug Use Indicators at Government Health Care facilities; A Hospital Based Prospective Analysis. J pharm Bioall Sci pharm Bioall Sci 2010 v.3(1);
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053516/

• Hettihewa Lukshmy Menik A randomized double blind clinical trial of commercial garlic on improvement of lung functions in asthmatic patients 2009. Proceedings of 6th Annual sessions University of Ruhuna page 16-9

• Lukshmy M. Hettihewa, Sudheera S. Jayasinghe, Thilak P. Weerarathna, Imendra Kotapola. (2008) Correlation between changes of blood pressure with insulin resistance in type 2 diabetes mellitus with 4 weeks of pioglitazone therapy. Int. J.Diab .develp. Ctries, vol 28; 1 26-30 pp This journal is included in science citation index expanded.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772002/

• Lukshmy M. Hettihewa, Lalith P Dharmasiri, Chamil D Ariyarathna, Sudheera S. Jayasinghe, Thilak P. Weerarathna, Imendra Kotapola. (2007) significant correlation between BMI/BW with insulin resistance by McA, HOMA and QUICKI indices after 3 months of pioglitazone therapy. Galle Med.jour 12;1 18-24.
http://ehealth.lk/gma/publication/2007/Articles.pdf

• M. Hettihewa, Shalika Palangasinghe, Sudheera S. Jayasinghe Sudari W. Gunasekara, Thilak P. Weerarathna, Imendra Kotapola. (2007) Lipid abnormalities in type 2 diabebtes mellitus patients in Sri Lanka G.M.Journ. 12; 1 pp 1-4
http://www.sljol.info/index.php/GMJ/article/view/1076/984

• Jayasinghe SS, Hettihewa LM, Gunasekara SW, Palangasinghe S, Weerarathna TP, Remission of Diabetes Mellitus for 5 months after the treatment with Pioglitazone for type 2 Diabetes Mellitus; case report (2006) G.M.Journ vol 11;01 pp 54-6.

• Lukshmy M. Hettihewa, Shalika Palangasinghe, Sudheera S. Jayasinghe Sudari W. Gunasekara, Thilak P. Weerarathna Comparison of insulin resistance by indirect methods – HOMA, QUICKI and McAuley – with fasting insulin in patients with type2 diabetes in Galle, Sri Lanka: A pilot study Authors Online J Health Allied Scs.2006; 1:2 URL http://www.ojhas.org/issue17/2006-1-2.html. This journal is indexed and peer review journal published more than two issues per year

• Hettihewa Luskhmy Menik, Jayasinghe Sudeera Sammanthi, Weerarathna Thilak Priyantha, Gunasekara Sudari Wijewickrama, Palangasinghe Shalika, Imendra Kotapola. Genetic association between insulin resistance and total cholesterol in 12 type 2 Diabetes Mellitus -A preliminary observation URL:
http://www.ojhas/issure13/2005-1-4.html

• Hettihewa L.M. Immunization of retrovirus transfected dendritic cells induces specific cytotoxic T lymphocytes for two distinct malarial peptides by Kd molecule. Journal of Immunopharmacology. 2003 Vol 3/10-11 pp 1401-1411. http://www.sciencedirect.com/science/article/pii/S1567576903001371 (Included in science citation index). It won the presidential award in 2003

• Lukshmy Menik Hettihewa. Use of genetic markers for identification of cells. GMJ 2004 9:1 20-1.30. Hettihewa L.M. (2003) Molecular Diagnostics in clinical Practice G.M.Journ Vol 4 (12-15)

• Lukshmy Hettihewa L.M, Fernando A, Pathirana C1998: Therapeutic evidence from human experiments of garlic and its important application in different disease entities. G.M.Journ. Vol 3(1) (5-7)


Oral Presentations


• 38 joint conferences on parasitic diseases by Japan- United States Cooperation Medical Science programme held in New Nagasaki Hotel, Japan in August 2002, . Hettihewa L.M. Induction of antigen specific CD 8+ T cells by immunization with genetically engineered dendritic cells expressing Malariasurface sporozoite protein 2 (SSP2).

• Genetic association of diabetes with insulin resistance in patients with type 2 diabetes Hettihewa L.M. Jayasinghe S.S. 2004 12-14 November Student Scientific Sessions Faculty of Medicine University of Colombo

• Comparison of insulin resistance by Mc Auley index and fasting insulin level in type II diabetes Hettihewa LM Palangasinghe 2004 12-14 November Student Scientific Sessions Faculty of Medicine University of Colombo

• Weerarathna TP, Hettihewa LM Jayasinghe SS and Imendra KG. Prevalence of Insulin resistance in individuals with type 2 Diabetes by different assessment methods. 118th SLMA annual sessions, March 2005

• Effects of Thiazide Diuretic On correlations among Blood Sugar, Insulin and Serum K+ levels in patients with Essential Hypertension Lukshmy M Hettihewa, Roshan Paranawithana, Nayana Weerasinghe, Nelka Warusavithana in annual academic sessions / University of Ruhuna November 2006

• Correlation between BMI and insulin resistance in type 2 diabetes patients on pioglitazone treatment. Hettihewa L.M. 2007, GMJ

• Lukshmy M Hettihewa, D. Liyanage, B. Sirisena, T.M. Minipura Casualty assessment and the severity of the adverse drug reactions (adr) actively detected in inward patients in tertiary care hospital sri lanka oral presentation at International conference of RISTON 2015 University of Ruhuna January 2015

• Evaluation of Anti-Oxidant Power of Flueggea leucopyrus Willd, a Medicinal Herb Used as Complementary Medicine for Cancer and Characterization of New AntiCancer Compounds”. ICNPDD 2016: International Conference on Natural Products and Drug Discovery in Kuala Lumpur, Malaysia Feb 11-12, 2016

Poster presentations
• Descriptive study o lipid profiles inpatients with type2 diabetes Mellitus Hettihewa LM, Gunasekara S.W 2004 12-14 November Student Scientific sessions, Faculty of Medicine University of Colombo

• Correlation between McAuley and lipoprotein ratios in the measurement of IR in non- obesed type 2 Diabetes (T2DM) Lukshmy M Hettihewa Thilak P Weerarathna, Sudheera S Jayasinghe, Kotapola G Imendra in annual 13 academic sessions / University of Ruhuna. November 2006

• Asian congress in autoimmunity 2009 presented the abstract as a poster on” High Maturation efficacy and MHC class I-peptide expression of bone marrow derived matured dendritic cells by antigen transfected retrovirus by IL-4” 4th Hettihewa L.M. Asian congress on Autoimmunity Singapore September 11-13 2009

• An analysis of drug use indicators in Government Health Care facilities in Galle Sri Lanka. Hettihewa L.M. Amrasinghe A.T.I.M, Subasinghe H.W.A.S National Medicine 26-28 May 2010 Australia

• Prospective encounter study on patient care indicators in health care facilities. Hettihewa L.M. Amarasinghe A.T.I.M, Subasinghe H.W.A.S ISPOR 4th Asia pacific Conference on 5-7 September 2010 Thailand

• Prolong expression of MHC class I molecules withhigh maturation efficacy of bone marrow derived retrovirus transfected dendritic cells by prolong centrifugation Hettihewa LM 14th international congress of autoimmunity Kobe Japan 22-27 August 2010

• prospective cross sectional surveillance on dispensing efficacy, drug availability and quality of labeling using patient care indicators in health care facilities in Galle district. Hettihewa LM, Jayarathna K 17th -23rd July 2010, Copenhagen, Denmark 2010

• Comparison of the knowledge in core policies of essential drug list among medical practitioners and medical students. Hettihewa L. M. Jayarathna K. 17th -23rd July 2010, Copenhagen, Denmark 2010

• Subasinghe HWAS, Gunawardana S and LIyanage T. Induction of insulin resistance/ impaired glucose tolerance in experimental wista rats fed on modified high fat diet regime. Oral presentation GMA session oct 2012

• Subasinghe HWAS, Gunawardana S and LIyanage T. Cumulative quantal dose responses of costus specious leaves on the lipid subprofile in high fat diet induced insulin resistant wistar rats. 6th asian association 14 of school of pharmacy conference, National University of Singapore. 14th – 17th November 2013

• Costus specious leave water extract reduces the atherogenic risk I high fat diet induced insulin resistant rats. 6th Asian association of school of pharmacy conference, National University of Singapore. 14th – 17th November 2013

• sandhya Nair1, Menik Hettihewa2 and H.P. Vasantha Rupasinghe. Leaf extract of Costus speciosus induces apoptosis in human hepato cellular carcinoma cells. Canadian cancer research conference Nov 3-6 in Toronto

• Subasinghe HWAS, Gunawardana S and LIyanage T. Quantal dose response relationaship of leave extracts of costus speciosus on achieving peripheral insulin sensitivity in high fat diet fed experiemental rat mode. 4th academic sessions. Post Graduate Institute of Medicine, Colombo, Sri Lanka. 17th – 19th July 2013

• M.T. Madushika, D.D.S. Liyanage, L.M. Hettihewa. Validity of glycaemic tests over insulin resistance indices in detecting peripheral insulin resistance in polycystic ovary syndrome – Sri Lankan Study International conference of RISTON 2015 University of Ruhuna January 2015


Dr. Gayani Liyanage


Full articles


• P.L. Gayani C. Liyanage, Sarath Lekamwasam, Thilak P. Weerathna. Validity of the Diabetic Neuropathy score and Diabetic Neuropathy Examination score as screening tools for the detection of distal symmetrical diabetic neuropathy. Journal of Diabetes, 2012 (4);64-265

• Weerarathna TP, Liyanage PLGC, Herath HMM. Association of male gender and younger age at diagnosis of diabetes mellitus with more atherogenic lipid profile. International Archives of Medicine, 2015, (8:176); 1-8

• Liyanage P.L.G.C. Vitamin D therapy on diabetic nephropathy. Ruhuna Journal of Medicine (FMAS), 2016(04: 01), 7-16

• Gayani C. Liyanage, Sarath Lekamwasam, Thilak P. Weerarathna, Chandrani E. Liyanage. Effects of high-dose parenteral vitamin D therapy on lipid profile and blood pressure in patients with diabetic nephropathy: A randomized double-blind clinical trial. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2017 (11S);S767-S770
• Thilak Priyantha Weerarathna, Herath Mudiyanselage Meththananda Herath, Gayani Liyanage. Prevalence of low HDL cholesterol and its associations among Sri Lankan patients with diabetes mellitus on statin therapy. Diabetes& Metabolic Syndrome: Clinical Research & Reviews Volume 2017(11);S253-S256

• Liyanage P, Lekamwasam S, Weerarathna TP, Liyanage C. Effect of vitamin D therapy on urinary albumin excretion, renal functions and plasma renin among patients with diabetic nephropathy; a randomized, double-blind clinical trial. Journal of Postgraduate Medicine2018 Jan – March 64 (1);10 -15

• Polwatta Liyanage Gayani Chandima Liyanage, Sarath Lekamwasam, Thilak Priyantha Weerarathna, Dodanduwa Waduge Shyaml Yashodara Srikantha. Prevalence of normoalbuminuric renal insufficiency and associated clinical factors in adult onset diabetes. BMC Nephrology 2018;19-200

• Thilak Weerarathna, Gayani Liyanage, Meththananda Herath, Miyuru Weerarathna, Isuru Amarasinghe. Value of Estimated Glomerular Filtration Rate and Albuminuria in Predicting Cardiovascular Risk in Patients with Type 2 Diabetes without Cardiovascular Disease. BioMed Research International Volume 2018, Article ID 8178043, 5 pages.

• Thilak Priyantha Weerarathna, Miyuru Kavinda Weerarathna, Vidarsha Senadheera, Herath Mudiyanselage Meththananda Herath, Gayani Liyanage. Association of Self-Reported Dietary and Drug Compliance with Optimal Metabolic Control in Patients with Type 2 Diabetes: Clinic-Based Single-Center Study in a Developing Country. Journal of Nutrition and Metabolism. 2018, Article ID 3421476. 5 pages

• Herath Mudiyanselage Meththananda Herath, Iroshani Kodikara, Thilak Priyantha Weerarathna, Gayani Liyanage. Prevalence and associations of non-alcoholic fatty liver disease (NAFLD) in Sri Lankan patients with type 2 diabetes: A single center study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews; 2019(13);246 -250

• Meththananda Herath, Thilak Weerarathna, Gayani Liyanage, Vidarsha Senadheera.Prevalence and Associations of Subclinical Peripheral Artery Disease among Patients with Type 2 Diabetes without Clinical Macrovascular Disease: International journal of preventive medicine 2019 June DOI: 10.4103/ijpvm.IJPVM_427_18

Oral Presentations
• TP Weerarathna, PLGC Liyanage, LS Basnayake. Prevalence of post prandial hyperglycemia and the value of assessing post prandial blood glucose in patient clinic. The 63rd annual academic session of Galle Medical Association September 2004(9:1)
• TP Weerarathna, LS Basnayake, PLGC Liyanage. Prevalence and pattern of diabetic dyslipidemia among newly diagnosed patients with type diabetes under the age of 40 years. The 63rd annual academic session of Galle Medical Association September 2004 (9:1)
• KD Pathirana, LS Basnayake , PLGC Liyanage. Prevalence of migraine among advanced level students. The 63rd annual academic session of Galle Medical Association September 2004(9:1)
• CK Bodhinayake, TP Weerarathna, PLGC Liyanage, Basnayake LS. Value of C-reactive protein in predicting adverse out comes in dengue fever. The Second Annual Academic Session of University of Ruhuna, Faculty of Medicine, December 2004.
• Kithsiri Dedduwa Pathirana, Basnayake LS, Liyanage PLGC. Prevalence of migraine among senior secondary school children in Sri Lanka. 11thAsian and Oceanic Congress of Neurology, Singapore 2004
• PLGC Liyanage, KD Pathirana, M Senaviratne, L Abeywardene, LS Basnayake. Feasibility of thrombolytic therapy at tertiary care centers in Sri Lanka. The annual academic session of Galle Medical Association 2005,54
• PLGC Liyanage, KD Pathirana, LS Basnayake. Precipitating factors of migraine in young migraine suffers in southern Sri Lanka. Galle Medical Association 2005;68
• K D Pathirana, K G Somasiri, R P Bandusiri, L S Basnayaka, P G L C Liyanage. Quality of life in patients opted for Botulinum Toxin injections for hemi-facial spasms. 38th Annual Academic Sessions Ceylon College of Physicians Sep. 2005, Page 38
• Liyanage PLGC, Lekamwasam S, Weerarathna TP. Validity of Diabetic Neuropathy Symptom (DNS) and Diabetic Neuropathy Examination (DNE) scores as screening tools of diabetic neuropathy., The annual academic sessions of Galle Medical Association, Galle Medical Journal, 2011(16:2);59
• Liyanage PLGC, Lekamwasam S, Weerarathna TP. Prevalence of autonomic neuropathy among diabetics attending medical clinics in Teaching Hospital Karapitiya The annual academic sessions of Galle Medical Association. Galle Medical Journal, 2011(16:2);60
• Liyanage PLGC, Lekamwasam S, Abeygunawardhana SNW, Weerarathna TP. Prevalence of periodontal disease in diabetic patients attending medical clinics, Teaching Hospital Galle. The Sri Lanka Medical Association (SLMA). The Ceylon Medical Journal, 2012(57:1), 21
• Liyanage PLGC, Lekamwasam S, Sathananthan PP Validation of a Sinhala Version of the WHO Rose Angina Questionnaire. The annual academic sessions of Ceylon College of Physicians (CCP) 2012;76-77
• TP Weerarathna, HMM Herath, PLGCLiyanage, Ariyaratne MHB.Prevalence and predictors of high density lipoprotein levels among individuals with type 2 diabetes. Theannual academic sessions Sri Lanka Medical Association 2012(57:1),20
• Weerarathna TP, Herath HMM, Liyanage PLGC, Ariyaratne MHB.Variation in the modifiable cardiovascular risk factors in different phenotypes of type 2 diabetes. The Sri Lanka Medical Association 2012 (57:1),22
• Liyanage PLGC, Lekamwasam S, Weerarathna TP, C Liyanage. Prevalence of normoalbuminuric renal insufficiency and associated clinical factors in adult onset diabetes. Theannual academic sessions of Galle Medical Association 2013(18:2);35
• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Comparison of Cockcroft-Gault and modification of diet in renal disease study equations in estimating glomerular filtration rate among patients with diabetes. The annual academic sessions of Galle Medical Association 2013(18:2);36
• Weerarathna TP, Herath HMM, Liyanage PLGC, Kariyawasam AGTA, Ganegoda VR. Prevalence and determinants of abnormalities in the resting electrocardiogram in subjects with diabetes. The 127th International Medical Congress of the Sri Lanka Medical Association in 2014
• Weerarathna TP, Herath HMM, Liyanage PLGC, Kariyawasam AGTA, Ganegoda VR. Association of carotid intima media thickness with calculated cardiovascular risk score in subjects with type 2 diabetes. The 127th International Medical Congress of the Sri Lanka Medical Association in 2014,115
• Dahanayake M, Rathnayake M, Edirisinghe U, Jayawardhana M, Bethmiarachchi D, Liyanage G, Weerarathna T. What anthropometric parameters and lipid parameters predict abnormal glucose tolerance in the first-degree relatives of patients with type 2 diabetes? Annual Academic Sessions, Anuradhapura Clinical Society, Anuradhapura, Sri Lanka; 2015(9)
• PLGC Liyanage, S Lekamwasam, TP Weerarathna T, C Liyanage. Effect of vitamin D therapy on bone mineral density among people with diabetic nephropathy; a randomized, double-blind placebo controlled clinical trial. Annual academic sessions of Galle Medical Association 2015(20:2);59
• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Effect of vitamin D therapy on bone mineral density among patients with diabetic nephropathy: a randomized, double-blind placebo controlled clinical trial. Osteoporos Int. 2015; 1: S230
• G Liyanage, S Lekamwasam, T Weerarathna, C Liyanage. Effect of vitamin D therapy on urinary albumin excretion, renal functions and plasma renin among patients with diabetic nephropathy; A randomized double-blind clinical trial. The 9th International Conference on Advanced Technologies and treatments for diabetes, Milan, Italy, 3-6 February 2016
• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Effects of six months, high dose parenteral vitamin D therapy on cardiovascular Risk Scores in patients with diabetic nephropathy; A randomized double blind placebo Controlled clinical trial. 14th Academic Sessions, University of Ruhuna, 1st March 2017
• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Nafla MNF, Srikantha DWSY. Prevalence of peripheral vascular disease among patients with diabetes attending medical clinics in Teaching Hospital Karapitiya. The annual academic sessions of Galle Medical Association 2017.
• PLAN Liyanage, PLGC Liyanage, GMP Sirimanna, N Schurer. Comparative study of skin lightening agents on skin of color. 9th Conference of Asian Society for Pigment Cell Research and 26th Annual Academic Sessons of Sri Lanka College of Dermatologists, 15th-18th August 2018,125
• Herath HMM, Kodikara I, Weerarathna TP, Liyanage G, Wickramathilake M. Diagnostic accuracy of aminotransferase as marker for nonalcoholic fatty liver disease among patients with type 2 diabetes mellitus. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);4
• Herath HMM, Kodikara I, Weerarathna TP, Liyanage G, Wickramathilake M. Prevelance and factors associated with nonalcoholic fatty liver disease among type 2 diabetes patients in Sri Lanka. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);14
• Liyanage PLGC, Prasanna HT, Lekamwasam S. Inappropriate prescribing in elderly attending medical clinics, Teaching Hospital Karapitiya; an analysis based on STOPP/START Criteria. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);17
• Lekamwasam Sarath, Liyanage Gayani, Impact of health literacy on patient centered care, 6th AHLA International Health Literacy Conference, Taichung, Taiwan DOI: 10.6881/AHLA.201810.SC03


Oral Presentations


• TP Weerarathna, PLGC Liyanage, LS Basnayake. Prevalence of post prandial hyperglycemia and the value of assessing post prandial blood glucose in patient clinic. The 63rd annual academic session of Galle Medical Association September 2004(9:1)

• TP Weerarathna, LS Basnayake, PLGC Liyanage. Prevalence and pattern of diabetic dyslipidemia among newly diagnosed patients with type diabetes under the age of 40 years. The 63rd annual academic session of Galle Medical Association September 2004 (9:1)

• KD Pathirana, LS Basnayake , PLGC Liyanage. Prevalence of migraine among advanced level students. The 63rd annual academic session of Galle Medical Association September 2004(9:1)

• CK Bodhinayake, TP Weerarathna, PLGC Liyanage, Basnayake LS. Value of C-reactive protein in predicting adverse out comes in dengue fever. The Second Annual Academic Session of University of Ruhuna, Faculty of Medicine, December 2004.

• Kithsiri Dedduwa Pathirana, Basnayake LS, Liyanage PLGC. Prevalence of migraine among senior secondary school children in Sri Lanka. 11thAsian and Oceanic Congress of Neurology, Singapore 2004

• PLGC Liyanage, KD Pathirana, M Senaviratne, L Abeywardene, LS Basnayake. Feasibility of thrombolytic therapy at tertiary care centers in Sri Lanka. The annual academic session of Galle Medical Association 2005,54

• PLGC Liyanage, KD Pathirana, LS Basnayake. Precipitating factors of migraine in young migraine suffers in southern Sri Lanka. Galle Medical Association 2005;68

• K D Pathirana, K G Somasiri, R P Bandusiri, L S Basnayaka, P G L C Liyanage. Quality of life in patients opted for Botulinum Toxin injections for hemi-facial spasms. 38th Annual Academic Sessions Ceylon College of Physicians Sep. 2005, Page 38

• Liyanage PLGC, Lekamwasam S, Weerarathna TP. Validity of Diabetic Neuropathy Symptom (DNS) and Diabetic Neuropathy Examination (DNE) scores as screening tools of diabetic neuropathy., The annual academic sessions of Galle Medical Association, Galle Medical Journal, 2011(16:2);59

• Liyanage PLGC, Lekamwasam S, Weerarathna TP. Prevalence of autonomic neuropathy among diabetics attending medical clinics in Teaching Hospital Karapitiya The annual academic sessions of Galle Medical Association. Galle Medical Journal, 2011(16:2);60

• Liyanage PLGC, Lekamwasam S, Abeygunawardhana SNW, Weerarathna TP. Prevalence of periodontal disease in diabetic patients attending medical clinics, Teaching Hospital Galle. The Sri Lanka Medical Association (SLMA). The Ceylon Medical Journal, 2012(57:1), 21

• Liyanage PLGC, Lekamwasam S, Sathananthan PP Validation of a Sinhala Version of the WHO Rose Angina Questionnaire. The annual academic sessions of Ceylon College of Physicians (CCP) 2012;76-77

• TP Weerarathna, HMM Herath, PLGCLiyanage, Ariyaratne MHB.Prevalence and predictors of high density lipoprotein levels among individuals with type 2 diabetes. Theannual academic sessions Sri Lanka Medical Association 2012(57:1),20

• Weerarathna TP, Herath HMM, Liyanage PLGC, Ariyaratne MHB.Variation in the modifiable cardiovascular risk factors in different phenotypes of type 2 diabetes. The Sri Lanka Medical Association 2012 (57:1),22

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, C Liyanage. Prevalence of normoalbuminuric renal insufficiency and associated clinical factors in adult onset diabetes. Theannual academic sessions of Galle Medical Association 2013(18:2);35

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Comparison of Cockcroft-Gault and modification of diet in renal disease study equations in estimating glomerular filtration rate among patients with diabetes. The annual academic sessions of Galle Medical Association 2013(18:2);36

• Weerarathna TP, Herath HMM, Liyanage PLGC, Kariyawasam AGTA, Ganegoda VR. Prevalence and determinants of abnormalities in the resting electrocardiogram in subjects with diabetes. The 127th International Medical Congress of the Sri Lanka Medical Association in 2014

• Weerarathna TP, Herath HMM, Liyanage PLGC, Kariyawasam AGTA, Ganegoda VR. Association of carotid intima media thickness with calculated cardiovascular risk score in subjects with type 2 diabetes. The 127th International Medical Congress of the Sri Lanka Medical Association in 2014,115

• Dahanayake M, Rathnayake M, Edirisinghe U, Jayawardhana M, Bethmiarachchi D, Liyanage G, Weerarathna T. What anthropometric parameters and lipid parameters predict abnormal glucose tolerance in the first-degree relatives of patients with type 2 diabetes? Annual Academic Sessions, Anuradhapura Clinical Society, Anuradhapura, Sri Lanka; 2015(9)

• PLGC Liyanage, S Lekamwasam, TP Weerarathna T, C Liyanage. Effect of vitamin D therapy on bone mineral density among people with diabetic nephropathy; a randomized, double-blind placebo controlled clinical trial. Annual academic sessions of Galle Medical Association 2015(20:2);59

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Effect of vitamin D therapy on bone mineral density among patients with diabetic nephropathy: a randomized, double-blind placebo controlled clinical trial. Osteoporos Int. 2015; 1: S230

• G Liyanage, S Lekamwasam, T Weerarathna, C Liyanage. Effect of vitamin D therapy on urinary albumin excretion, renal functions and plasma renin among patients with diabetic nephropathy; A randomized double-blind clinical trial. The 9th International Conference on Advanced Technologies and treatments for diabetes, Milan, Italy, 3-6 February 2016

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Effects of six months, high dose parenteral vitamin D therapy on cardiovascular Risk Scores in patients with diabetic nephropathy; A randomized double blind placebo Controlled clinical trial. 14th Academic Sessions, University of Ruhuna, 1st March 2017

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Nafla MNF, Srikantha DWSY. Prevalence of peripheral vascular disease among patients with diabetes attending medical clinics in Teaching Hospital Karapitiya. The annual academic sessions of Galle Medical Association 2017.
• PLAN Liyanage, PLGC Liyanage, GMP Sirimanna, N Schurer. Comparative study of skin lightening agents on skin of color. 9th Conference of Asian Society for Pigment Cell Research and 26th Annual Academic Sessons of Sri Lanka College of Dermatologists, 15th-18th August 2018,125

• Herath HMM, Kodikara I, Weerarathna TP, Liyanage G, Wickramathilake M. Diagnostic accuracy of aminotransferase as marker for nonalcoholic fatty liver disease among patients with type 2 diabetes mellitus. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);4

• Herath HMM, Kodikara I, Weerarathna TP, Liyanage G, Wickramathilake M. Prevelance and factors associated with nonalcoholic fatty liver disease among type 2 diabetes patients in Sri Lanka. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);14

• Liyanage PLGC, Prasanna HT, Lekamwasam S. Inappropriate prescribing in elderly attending medical clinics, Teaching Hospital Karapitiya; an analysis based on STOPP/START Criteria. 77th Annual academic sessions of the Galle Medical association 10th-12th October 2018(23:1);17

• Lekamwasam Sarath, Liyanage Gayani, Impact of health literacy on patient centered care, 6th AHLA International Health Literacy Conference, Taichung, Taiwan DOI: 10.6881/AHLA.201810.SC03


Poster Presentations


• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C, Prevalence of diabetic nephropathy among diabetics attending medical clinics, Teaching Hospital Galle. The annual academic sessions of Ceylon College of Physicians (CCP) 2012;68
• Liyanage PLGC, Liyanage C, Lekamwasam S, Weerarathna TP, Sirisena AHBA. Adherence to American Diabetes Association (ADA) dietary recommendations among patients with diabetes attending medical clinics in Teaching Hospital Galle. Poster presentation, Galle Medical Association. Galle Medical journal, Oct 2012(17:2);68

• G Liyange, S Lekamwasam, C Liyanage, T Weerarathna. Vertebral fractures among adult diabetics: Prevalence and Risk factors. The 3rd Asia pacific Osteoporosis Meeting, Kuala lumpur, Malaysia 2012. Osteoporos Int. 2012(7);S772-S773

• Liyanage PLGC, Lekamwasam S, Weerarathna TP, Liyanage C. Effects of six months, high dose parenteral vitamin D therapy on lipid pro-file and blood pressure in patients with diabetic nephropathy; A randomized double-blind clinical trial. Presented at 16th Annual Academic Sessions and Sri Lanka intervention meeting of Sri Lanka Heart Association. Colombo Sri Lanka, June 2016;39

• Nafla MNF, Srikantha DWSY, Amarasinghe ATIM, Liyanage PLGC, Jayasinghe SS, Active surveillance of adverse drug reactions–severity and triggering drugs. 76th Annual Academic Sessions of the Galle Medical Association 11th -13th October 2017; 64

• Srikantha DWSY, Nafla MNF, Amarasinghe ATIM, Liyanage PLGC, Jayasinghe SS, Active surveillance of adverse drug reactions in Teaching Hospital Karapitiya for a six month period. 76th Annual Academic Sessions of the Galle Medical Association 11th -13th October 2017; 864

• Liyanage PLGC, Dasanayake DLW, Ponnamperuma T. Effectiveness of misoprostol in the managements of miscarriages, in patients admitted to Teaching Hospital, Mahamodara. 51st Annual Scientific Congress, Sri Lanka College of Obstetricians and Gynaecologists, August 2018(40:1);79-80)

• Jayaweera LJ, Liyanage PLGC, Kumarasinghe P. A study of the outcomes of dengue infection in patients with diabetes mellitus. Sri Lanka Medical Association131st Annual International Medical Congress, 2018(63:1);125-126)


Prof.  Sudheera Jayasinghe


Full articles


• Jayasinghe S.S, Senevirathne S.A. Neurotoxic effects of paraquat: A mini review. The Galle Medical Journal (2016); 21 (2): 21-24

• Pallagae Mangala C. S. De Silva, Khaja Shameem Mohammed Abdul , Eakanayake M. D. V. Eakanayake, Sudheera Sammanthi Jayasinghe, Channa Jayasumana, Hewa Bandulage Asanthi, HettiarachigaeS. D. Perera, Gamage G. Tushara Chaminda, Ediriweera P. S. Chandana, Sisira H. Siribaddana. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communitiesin Sri Lanka. PLoS Negl Trop Dis (2016); 10(9): e0004979.

• Jayasinghe S S. Effects of acute organophosphate or paraquat exposure on neuromuscular function and efficacy of antioxidant therapy in acute paraquat poisoning. Ruhuna Journal of Medicine (2015); 3(1): 1-13

• Khaja Shameem Mohammed Abdula, Sudheera Sammanthi Jayasinghe, Ediriweera P. S Chandana, Channa Jayasumana, P. Mangala C.S. De Silva. Arsenic and human health effects: A Review. Environmental Toxicology and Pharmacology (2015). 40 828–846

• Jayasinghe SS, Fernando A. Adherence to the current guidelines in the management of paraquat poisoning; an audit. The Galle Medical Journal (2013); 18 (2): 13-16

• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana. Slow Repetitive Nerve Stimulation in Patients with Acute Organophosphorus Poisoning after Clinical Recovery. Asia pacific Journal of Medical Toxicology (2013); 2 (1): 14-18

• SS Jayasinghe, S Lekamwasam, DCL De Silva, TSD Amarasena, L Subasinghe, N Purasinghe. Short Research Communication: Predicting osteopathy among patients with thalassaemia major using selected clinical and biochemical information. The Galle Medical Journal (2012); 17 (2): 8-11

• Sudheera S. Jayasinghe, Kithsiri D. Pathirana, Nick A. Buckley. Effects of Acute Organophosphorus Poisoning on Function of Peripheral Nerves: A Cohort Study. PLOS ONE (2012); 7 (11): e49405

• Jayasinghe SS, Pathirana KD, Vimalasena GTHIP, Tharanga D. Hearing impairment in children following bacterial meningitis; assessed with brainstem auditory evoked response (BSAER). The Galle Medical Journal (2012); 17 (1): 1-4

• Jayasinghe SS, Fernando A. Adherence to the National Guidelines on the Management of Organophosphorus Poisoning. The Galle Medical Journal (2012); 17 (1): 37-42

• Jayasinghe SS. Effects of acute organophosphate ingestion on cognitive function, assessed with the mini mental state examination. Journal of Postgraduate Medicine (2012); 58 (3): 171-175

• Sudheera S. Jayasinghe, Kithsiri D. Pathirana. Autonomic Function following Acute Organophosphorus Poisoning: A Cohort Study. PLoS ONE (2012); 7 (5): e37987

• Klientan Wunnapuk, Gregory A. Medley, Xin Liu, Jeffrey E. Grice, Sudheera Jayasinghe, Indika Gawarammana, Nicholas A. Buckley, Michael S. Roberts. Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B (2011); 879 (28): 3047-3052

• S S Jayasinghe. Psychological distress among patients with organophosphorus or paraquat poisoning. The Galle Medical Journal (2011); 16 (2): 8-12

• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana. Effects of Deliberate Ingestion of Organophosphate or Paraquat on Brain Stem Auditory-Evoked Potentials. J. Med. Toxico (2011); 7 (4): 277-280

• Jayasinghe S S, Fernando A, Pathirana KD, K Kishanthi Gunasinghe. Atropine therapy in acute anticholinesterase (Organophosphorus / Carbamate) poisoning; adherence to current guidelines. The Galle Medical Journal (2009); 14 (1): 26-30

• L M Hettihewa, S S Jayasinghe, K G Imendra, T P Weerarathna. Correlation between changes of blood pressure with insulin resistance in type 2 diabetes mellitus with 4 weeks of pioglitazone therapy. Int Diab Dev Ctries (2008); 28 (1): 26-30

• Lukshmy M. Hettihewa, Lalith P. Dharmasiri, Chamil D. Ariyarathne, Sudheera S. Jayasinghe, Thilak P. Weerarathna, Imendra G. Kotapola. Significant correlation between BMI/BW with insulin resistance by McAuley, HOMA and QUICKI indices after 3 months of pioglitazone in diabetic population. Int J Diab Dev Ctries (2007); 27 (3): 87-92

• Lukshmy Menik Hettihewa, Sudari Wijewickrama Gunasekera, Sudheera Sammanthi Jayasinghe, Shalika Palangasinghe, Thilak Priyantha Weerarathna, Imendra Kotapola. Lipid abnormalities in type 2 diabetes mellitus patients in Sri Lanka. The Galle medical journal (2007); 12 (1): 1-4

• Lukshmy M Hettihewa, Lalith P Dharmasiri, Chamil D Ariyaratne, Sudheera S Jayasinghe, Thilak P Weerarathna, Imendra G Kotapola. Correlation between BMI and insulin resistance in type 2 diabetes mellitus patients on pioglitazone treatment. The Galle medical journal (2007); 12 (1): 18-24

• Hettihewa L. M, Palangasinghe S, Jayasinghe S. S, Weerarathna T. P, Gunasekara S. W. Comparison of insulin resistance by indirect methods – HOMA, QUICKI and McAuley – with fasting insulin in patients with type 2 diabetes in Galle, Sri Lanka: A pilot study. Online J Health Allied Scs (2006);1:2
URL http://www.ojhas.org/issue17/2006-1-2.htm

• S.S Jayasinghe, L.M Hettihewa, S.W Gunasekera, S Palangasinghe, K.G Imendra, T.P Weerarathna. Remission of diabetes mellitus after treatment with Pioglitazone. The Galle medical journal (2006); 11(1): 54-56

• Hettihewa L. M, Jayasinghe S. S, Weerarathna T. P, Gunasekara S. W, Palangasinghe S, Imendra K . Genetic association between Insulin resistance and total cholesterol in Type 2 Diabetes Mellitus- A preliminary observation. Online J Health Allied Science (2005); 1:4
URL http://www.ojhas.org/issue 13/2005-1-4.htm


Oral presentations


• Khaja Abdul, Sudheera Jayasinghe, Saman Chandana, Channa Jayasumana, Sisisrs Siribaddana, Mangala de Silva. Occupational glyphosate exposure and its association with urinary renal injury biomarker (NGAL) among sugarcane farmers in Sri Lanka. 16th Annual Scientific Congress of the Asia Pacific Association of Medical Toxicology, November 2017; 129
• Paherathy A, Galappatthy P, Sri Ranganathan S, Amarasinghe ATIM, Rameshkumara T, Haputhanthrige UI, Jayasinghe S, Jayakody RL. Analysis of adverse drug reaction reports received by a central monitoring centre. Scientific Sessions of the Sri Lanka Association of Clinical Pharmacology and Therapeutics, 13th-14th October 2017; 29
• Dilini V. Ekanayake, Khaja S. Mohammed Abdul, Wanniarachchi A.K.G. Thakshila, HewabandulageAsanthi, ChannaJayasumana, Sudheera S. Jayasinghe, Ediriweera P. S. Chandana, Sisira H. Siribaddana, Mangala C. S. De Silva, Urinary biomarkers KIM-1 and NGAL may predict Chronic Kidney Disease of uncertain etiology (CKDu) among Sugarcane farmers in Sri Lanka. 10th International Research Conference of the General Sir John KotelawalaDefense University Sri Lanka 3rd – 4th August 2017
• Sudheera Jayasinghe, Fathima Shihana, Nick Buckley, Andrew Dawson, Klintean Wunnapuk. Antioxidant therapy on paraquat induced pulmonary injury; quantified with human clara cell protein ELISA. 15th Asia Pacific Medical Association of Medical Toxicology International Scientific Conference. 17th-20th November 2016 Singapore; 79
• Wanni Arachchi T.I, gamage M.W.K, Jayasinghe S.S. Administration of paracetamol for childhood fever, practices of parents. Fourth Faculty of Medicine Academic Sessions 15th November 2016. Ruhuna Journal of Medicine (2016). 4 (1);41
• K.S Mohammed Abdul, C. Jayasumana, S.H Siribaddana, S.S Jayasinghe, H.B Asanthi, G.G.T Chaminda, E.P.S. Chandana, P.Mangala C.S De Silva. Urinary biomarkers KIM-1 and NGAL for early prediction of Chronic Interstitial Nephritis in Agricultural communities in Sri Lanka. Second International workshop on Mesoamerican Nephropathy held at San Jose, Costa Rica. (2015)
• S Jayasinghe. Neurophysiology in acute organphosphate poisoning: Experience in Sri Lanka. Seventh Annual scientific sessions of the Association of Sri Lankan Neurologists. (2013) ; (28)
• Jayasinghe S S, Dawson A H, Buckley N, Fernando A. Effect of antioxidants (vitamin C and n-acetylcysteine) on the outcome of acute paraquat poisoning. The Gall Medical Journal (2013); 18(2): 38
• Jayasinghe S S, Pathirana K D. Neuro-muscular junction dysfunction in paraquat survivors. The Galle Medical Journal (2013); 18(2): 39
• S S Jayasinghe. Peripheral nerve function in paraquat survivors. Ceylon Medical journal (2012); 51
• Jayasinghe S S, Fernando A. Adherence to the National guidelines on the administration of Fuller’s earth in the management of paraquat poisoning. The Galle Medical journal (2011); 16 (2): 53-54
• Jayasinghe S S, Pathirana K D, Vimalasena G T I P, Tharanga D. Hearing impairment in children following bacterial meningitis; assessed with brainstem auditory evoked response (BSAER). The Galle Medical journal (2011); 16 (2): 53
• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana. Autonomic dysfunction in paraquat survivors. 9th congress of Asia Pacific Association of Medical Toxicology, Hanoi, Vietnam, November 17th – 19th 2010: 71
• Jayasinghe SS, Pathirana KD. Subclinical nerve fiber dysfunction following acute organophosphate (OP) poisoning. 2010 North American Congress of Clinical Toxicology Annual Meeting, Denver, CO, USA, October 7-12, 2010; 48 (6):604
• Jayasinghe SS, Pathirana KD, Gunasinghe KK. Normative values of motor and sensory nerve conduction studies. The Galle Medical Journal (2010); 15 (1): 43
• Amila KA, Palangasinghe C, Abeygunarathna G, Gunasekera C, Jayasinghe SS, Ariyananda PL. Pattern of mortality and morbidity following self ingestion of potassium permanganate and oxalic acid containing household detergents in Southern Sri Lanka. The Galle Medical Journal (2010); 15 (1): 53
• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana, Kaluthotage Kishanthi Gunasinghe. Assessment of Neuromuscular Junction (NMJ) function by slow repetitive stimulation in patients following acute organophosphorus poisoning. 8th congress of Asia Pacific Association of Medical Toxicology, Beijing China, October 19th – 22nd, 2009: 90
• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana, Kaluthotage Kishanthi Gunasinghe. Sympathetic Skin Response (SSR) and Heart Rate Variability in patients with acute organophosphorus (OP) poisoning. 8th congress of Asia Pacific Association of Medical Toxicology, Beijing China, October 19th – 22nd, 2009: 43
• Jayasinghe SS, Dawson AH , Pathirana K. Assessment of autonomic function in patients with acute anticholinesterase poisoning. 7th congress of Asia Pacific Association of Medical Toxicology, Chandigarh, India, December 7-10, 2008
• Jayasinghe SS, Pathirana KD. Prevalence of psychological distress in patients with self ingestion of anticholinesterase. Galle Research Network Academic Day 2008 (18th November 2008), Faculty of Medicine, University of Ruhuna
• Lukshmy M. Hettihewa, Lalith P. Dharmasiri, Chamil D. Ariyaratne, Sudheera S. Jayasinghe, Thilak P. Weerarathna, Significant weight gain of female patients compared to male after one year of pioglitazone therapy in non-obese type 2 diabetes mellitus. Foundation session of Kandy Society of Medicine 18th August 2006
• Jayasinghe S. S, Gunasekara S. W, Palangasinghe S, Samaranayaka N, Hettihewa L. M, Weerarathna T. P. Genetic association of Diabetes with Insulin Resistance in patients with type 2 Diabetes; Preliminary study. Student Scientific Sessions 2004 (12-14 November), Faculty of Medicine, University of Colombo, Sri Lanka
• Palangasinghe S, Jayasinghe S.S, Gunasekera S.W, Samaranayaka N, Hettihewa L. M, Weerarathna T. P. Comparison of Insulin resistance by Mc Auley index and fasting insulin level alone in type 2 diabetes mellitus. Student Scientific Sessions 2004 (12-14 November), Faculty of Medicine, University of Colombo, Sri Lanka


Poster presentations


• Nafla MNF, Srikantha DWSY, Amarasinghe ATIM, Liyanage PLGC, Jayasinghe SS, Active surveillance of adverse drug reactions–severity and triggering drugs. 76th Annual Academic Sessions of the Galle Medical Association 11th -13th October 2017;64
• Srikantha DWSY, Nafla MNF, Amarasinghe ATIM, Liyanage PLGC, Jayasinghe SS, Active surveillance of adverse drug reactions in Teaching Hospital Karapitiya for a six month period. 76th Annual Academic Sessions of the Galle Medical Association 11th -13th October 2017; 864
• Dilini V. Ekanayake, Khaja S. Mohammed Abdul, Wanniarachchi A.K.G. Thakshila, HewabandulageAsanthi, ChannaJayasumana, Sudheera S. Jayasinghe, Ediriweera P. S. Chandana, Sisira H. Siribaddana, Mangala C. S. De Silva. Occupational herbicide exposure may induce kidney injury molecule I (KIM I) and Neutrophil Galatinase Associated Lipocalin (NGAL) levels in sugarcane farmers in rural Sri Lanka. The 29th Annual Scientific Conference of the International Society of Environmental Epidemiology, 24th-28th September 2017 Sydney, Australia; 274
• WAKG Thakshila, EMDY Ekanayake, BMM Rajapaksha, H Asanthi, SS Jayasinghe, EPS Chandana, C Jayasumana, AG Bandaranayake, PMCS De Silva. Fluoride in drinking water may not induce CKDu among rural paddy farmers in Southern Sri Lanka. 5th International Conference Sustainable Agriculture, Food and Energy, 22nd-24th August 2017 Malaysia; 91
• EMDV Ekanayake, WAKG Thakshila, TSK Dharmasiri, MAGD Samanmali, SS Jayasinghe, EPS Chandana, C Jayasumana, SH Siribaddana, PMCS De Silva. Emerging Chronic Kidney Disease of unknown etiology in paddy and sugarcane farmers in two adjacent provinces, Sri Lanka, 5th International Conference Sustainable Agriculture, Food and Energy, 22nd-24th August 2017 Malaysia; 92
• Jayasinghe S, Shihana F, Fernando A, Dawson A, Buckley N, Wunnapuk K. Lung biomarkers in patients treated with antioxidants following acute paraquat poisoning. Inaugural Academic Sessions of the Sri Lanka Association of Clinical Pharmacology and Therapeutics. (2016); (34)
• S S Jayasinghe. Electrophysiological evaluation of function of peripheral nerves & neuromuscular junction following acute organophosphorus over dose: A cohort study. Seventh Annual Scientific sessions of the Association of Sri Lankan Neurologists. (2013); (55)
• Ranasinghe N J, Egogage C G, Palangasinghe C, Dissanayake A S, Jayasinghe S S. The frequency and effect of home therapeutic measures in acute poisoning: A cross- sectional study. The Galle Medical Journal (013); 18(2): 58
• S Jayasinghe, S Lekamwasam, C de Silva, S Amarasena, D Tharangani. Prevalence and clinical predictors of osteopathy among thalassemics aged 4-25 years. Osteoporosis Int (2012); 23 (7): s770
• Jayasinghe SS. Normative values of autonomic function tests. The Galle Medical Journal (2012); 17 (2): 66
• Jayasinghe S S, Pathirana K D. Normative values of brain stem auditory evoked response (BAER). Association of Srilankan Neurologists, Fifth annual scientific sessions, Colombo, Sri Lanka, December 2nd – 4th 2011: P-24
• Sudheera S Jayasinghe, Kithsiri Dedduwa Pathirana. Effects of deliberate ingestion of organophosphate or paraquat on brain stem auditory evoked potentials. Association of Srilankan Neurologists, Fifth annual scientific sessions, Colombo, Sri Lanka, December 2nd – 4th 2011: P-25
• Sudheera S Jayasinghe, Nick A Buckley, Kithsiri D Pathirana. Peripheral nerve function in paraquat survivors. 10th congress of Asia Pacific Association of Medical Toxicology, Penang, Malaysia, November 11th – 14th 2011: 158-159
• Sudheera S Jayasinghe, Kithsiri D Pathirana, Nick A Buckley. Subclinical neuromuscular junction dysfunction following self-poisoning with paraquat. 10th congress of Asia Pacific Association of Medical Toxicology, Penang, Malaysia, November 11th – 14th 2011: 159
• Sudheera Sammanthi Jayasinghe, Nick Buckley, Andrew Hamilton Dawson, Anoja Fernando. Effects of intravenous vitamin C & N-acetylcysteine in acute paraquat poisoning. 9th congress of Asia Pacific Association of Medical Toxicology, Hanoi, Vietnam, November 17th – 19th 2010: 180-181
• S S Jayasinghe, K D Pathirana. Normative values of sympathetic skin response (SSR) and correlation of SSR with R-R interval based autonomic function tests. 29th International Congress of Clinical Neurophysiology, Kobe, Japan, October 28- November 1, 2010; 121(1): S113
• S S Jayasinghe, K D Pathirana. Autonomic dysfunction in patients with acute paraquat poisoning. Journal of the neurological sciences (2009); 285 (1): S321. 19th World Congress of Neurology, Bangkok, Thailand, 24th – 30th October 2009
• Sudheera Sammanthi Jayasinghe, Kithsiri Dedduwa Pathirana. Autonomic dysfunction in patients with acute anticholinesterase poisoning. Clinical neurophysiology (2009); 120 (1): S46. Asian and Oceanian Congress of Clinical Neurophysiology, Seoul, Korea. April 15- 18, 2009
• Kithsiri Dedduwa Pathirana, Sudheera Sammanthi Jayasinghe, Sujeewa C Atapattu, Hirumi Chandrasena, Chathrika Kodippili. Distal latency to second lumbrical as a measurement of severe carpal tunnel syndrome. Clinical neurophysiology (2009); 120 (1): S37. Asian and Oceanian Congress of Clinical Neurophysiology, Seoul, Korea, April 15- 18, 2009
• Kithsiri Dedduwa Pathirana, Sudheera Sammanthi Jayasinghe, Sujeewa C Atapattu, W.A.H.S Chandrasena, H.K.R Chathurika. Site of maximum slowing of sensory nerve conduction velocities in patients with mild and moderately severe Carple Tunnel Syndrome. Clinical neurophysiology 2009; 120 (1), S54. Asian and Oceanian Congress of Clinical Neurophysiology, Seoul, Korea, April 15- 18, 2009
• Jayasinghe SS, Dawson AH, Buckley NA, Pathirana K, Fernando A. Current practice of atropine therapy in acute cholinesterase inhibitor pesticide poisoning. 7th congress of Asia Pacific Association of Medical Toxicology, Chandigarh, India, December 7-10, 2008.
• Sudheera S Jayasinghe, Sarath Lekamwasam, T.S.D Amarasena, P.G.D Tharangani, P.N Dilrukshi, D.C.L De Silva. Prevalence and clinical predictors of osteopathy among thalassemics aged 4 – 25 years. IOF World Congress on Osteoporosis, Bangkok, Thailand, December 3-7, 2008
• Lukshmy M. Hettihewa, Thilak P. Weerarathna, Sudheera S. Jayasinghe, Kotapola G. Imendra. Correlation of insulin resistance by McAuley and lipoprotein ratios in non- obese Type 2 Diabetics (T2DM). 4th academic session, University of Ruhuna, November 2006
• Weerarathna T. P, Hettihewa L, Jayasinghe S. S, Gunasekara S. W, Palangasinghe S. Prevalence of Insulin Resistance Syndrome (IRS) in patients with Type 2 Diabetes according to criteria used by The American College of Endocrinologists (ACE) and their validity against indices of insulin resistance. 118th Anniversary Academic Sessions, Sri Lanka Medical Association, March 23-26, 2005
• Gunasekara S. W, Jayasinghe S. S, Palangasinghe S, Weerarathna T. P, Hettihewa L. M. Descriptive study of Lipid profile in patients with Type 2 Diabetes Mellitus. Student Scientific Sessions, Faculty of Medicine, University of Colombo, Sri Lanka, 12-14 November 2004; P-64


Dr. Isuru Amarasinghe


Full articles


• Thilak Weerarathna, Gayani Liyanage,Meththananda Herath,Miyuru Weerarathna,and Isuru Amarasinghe ; Value of Estimated Glomerular Filtration Rate and Albuminuria in Predicting Cardiovascular Risk in Patients with Type 2 Diabetes without Cardiovascular Disease. BioMed Research International Volume 2018, Article ID 8178043, 5 pages
• Hettihewa L Menik, Amrasinghe Isuru, and Subasinghe Sewwandi; Precepts and practices in drug use indicators at Government Healthcare Facilities: A Hospital – based prospective analysis. J pharm Bioail Sci 2011;1:165-9J Pharm Bioallied Sci. 2011 JanMar; 3(1): 165–169.
• Lukshmy Menik Hettihewa, Amarasinghe Isuru, and Jayarathna Kalana; Prospective encounter study of the degree of adherence to patient care indicators related to drug dispensing in Health Care facilities : A Sri Lankan perspective.J pharm Bioallied Sci 2011 Apr – Jun; 3(2):298-301
• Hettihewa Lukshmy Menik, Amrasinghe Isuru, and Subasinghe Sewwandi; Percept and practices in drug use indicators at Government Health care facilities: Hospital based prospective analysis. Indian J Pharmacol.2011;43:88-89
• Effects of metformin and lifestyle modifications on the progression of atherosclerosis among individuals with impaired glucose tolerance
Clinical trial Registration No: SLCTR/ 2016/026
Universal trial number – U1111-1183-4418


Oral presentation


• Effects of Metformin for six months on Glycaemic state, Lipid profile and anthropometry among individuals with Pre-diabetes, Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M, 17th Academic Sessions- University of Ruhuna- March 2020


Poster presentation


• Prospective encounter study on patient care indicators in health care facilities Hettihewa L.M, Amarasinghe A.T.I.M, Subasinghe H.W.A.S, ISPOR 4th Asia pacific Conference on 5-7 September 2010 Thailand
• Age and Gender difference in pre-diabetes and diabetes: A cross sectional community study in Galle district Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M , Endocrine Congress of Sri Lanka 2017
• Gender difference in subclinical atherosclerosis and macro vascular complications of diabetes mellitus; A single center, cross sectional study in Galle ATIM Amarasinghe, S.K.Y.I. Kodikara, MK Weerarathna, VR Senadeera, TCK Wimalarathna, GAU Shrimal , Endocrine Congress of Sri Lanka 2018
• Demographic and biochemical characteristics of individuals who have progressed to prediabetes from normal glucose tolerance during six months follow up Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M , 131st Anniversary International Medical Congress of Sri Lanka Medical Association 2018.
• Association between atherosclerosis and conventional cardiovascular risk factors among non-diabetic adults, Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M Endocrine Congress of Sri Lanka 2019
• Effects of a pre-designed exercise program of six months on weight , blood pressure , glycemic state and lipid profile among individuals with pre-diabetes, Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M , 3 rd annual academic sessions of Sri Lanka College of Internal Medicine 2019 Oral presentations:
• Which cardiovascular disease risk estimation tool would suit best to detect underlying atherosclerosis for Sri Lankan adults? Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M , 131st Anniversary International Medical Congress of Sri Lanka Medical Association 2018.
• Subclinical Atherosclerosis Among Individuals with Pre-diabetes A.T.I.M. Amarasinghe , S. Lekamwasam and T.P. Weerarathna , 15th Academic Sessions of University of Ruhuna, 2018
• Association of different metrics of glycosylated heamoglobin with sub-clinical atherosclerosis in patients with long-standing type 2 diabetes, Amarasinghe ATIM , Kodikara SKYI , Weerarathne TP, Weerarathne MK, Senadeera VR, Endocrine Congress of Sri Lanka 2019
• Compared to Exercise and Metformin alone, combination of treatment for six months for patients with Pre-diabetes helps to maintain sustained weight loss, Amarasinghe ATIM , Lekamwasam S, Weerarathna TP, Sumanathillake M, 17th Academic Sessions- University of Ruhuna- March 2020


Dr. R.A. Wasana Sevwandi


Oral Presentations


• Self-medication practice among pharmacy students in Sri Lanka. Sevwandi R.A.W., Sinhawansa M.Z., Tobgay S., Sri Ranganathan S., Annual Scientific Session 2016. Sri Lanka Association of Clinical Pharmacology and Therapeutics. 11th June 2016


Poster Presentations


• Localization value of distal latency to second lumbrical measurements in patients with carpal tunnel syndrome. Pathirana K.D., Sevwandi R.A.W., 76th Annual Academic Sessions 2017. Galle Medical Association
• High prevalence of anxiety and depression among patients with dengue and non-dengue acute febrile illness in Sri Lanka. C.K. Bodinayake, G.L. Tillekeratne, W.S. Ranaweera Arachchige, A.H. Pushpakumara, P.K. Wijayaratna, B.N. Jayasekara. – American Society of Tropical Medicine and Hygiene – Annual Meeting- 2018
• Analysis of 75 consecutive patients admitted with road traffic accidents (RTA) to a single surgical unit at GH Matara 08/02/2019 to 21/04/2019 W A K Weerawardena, S C Ubayasirinarayana, M S C Buddhika, S J Jayawickrama, K L Chaminda, U G A T Nayomi, W A D M Madubashini, R A W Sevwandi, K A L Asanka Surgery Unit A, General Hospital (GH) Matara. Sri Lanka Surgical Congress – 2019
• Anxiety and depression associated with dengue and other acute febrile illnesses among hospitalized patients in a medical unit in Teaching Hospital, Karapitiya. Bodinayake CK, Sevwandi RAW, Pushpakumara APARH, Wijayarathna PKPI, Jayasekara NABW, Colombo Medical Congress 2020, 14th February 2020


Dr. M. T. Madhushika


Full Article


• Liyanage, P.L.G.C., Lekamwasam, S., Weerarathna, T.P. and Madhushika, MT., 2016.Vitamin D and diabetes; a review. Galle Medical Journal, 20(2).

• Wijesundara, W.M.H., Sujeewan, P.J., Madhushika, M.T., Rajapaksha, R.M.P.C.K.,2017.Revisiting self-poisoning Ampara; a descriptive study.Gal oya nimna clinicalsocity-10th Annual Scientific Session, 22(2).


Oral presentation


• Lukshmy M Hettihewa, D. Liyanage, B. Sirisena, T.M. Minipura Casualty assessment and the severity of the adverse drug reactions (adr) actively detected in inward patients in tertiary care hospital sri lanka oral presentation at International conference of RISTON 2015 University of Ruhuna January 2015


Poster presentation


• M.T. Madushika, D.D.S. Liyanage, L.M. Hettihewa. Validity of glycaemic tests over insulin resistance indices in detecting peripheral insulin resistance in polycystic ovary syndrome – Sri Lankan Study International conference of RISTON 2015 University of Ruhuna January 2015


Dr. Sahan Achintha Mendis


• Mendis SA, Meegahapola H, Mathotaarachchi S; Knowledge, attitude and practice of primary wound care in prevention of Rabies: A descriptive cross sectional study in Colombo – Poster presentation at 126th Anniversary Scientific Congress, Sri Lanka Medical Association, 9th July to 13th July, 2013.

• Mendis SA, Mahipala JRG, Weerakoon B, Amarasinghe A, Korelage HT; Diagnosis of Dengue: A diagnostic accuracy study in Colombo – Oral presentation at International Conference on public health innovations, National Institute of Health Sciences, Sri Lanka, 2nd May to 4th May, 2013.

• Mendis SA, Mahipala JRG, Weerakoon B, Mahdoom A, Amarasinghe A, Korelage HT; Comparison of clinical and laboratory diagnosis of Dengue: Activated passive surveillance in Colombo, Sri Lanka – Oral presentation at 18th Annual Academic Sessions, College of Community Physicians of Sri Lanka, 1st September 2013.

• Mendis SA, Mahipala JRG, Weerakoon B, Amarasinghe A, Korelage HT; Heamorrhagic manifestations and their relationship with the associated factors and the disease outcome in dengue fever/dengue hemorrhagic fever – Poster presentation at 4th PGIM academic sessions, Postgraduate Institute of Medicine, University of Colombo, 17th to 19th July 2013.

• Karunarathna AKTM, Mendis SA, Kulathunga A; Melloidosis complicated by infective sacroillitis in Sri Lanka, Journal of Tropical medicine, Travel Medicine and Vaccines, Bio Med Central 2018 Sep 19;4:12.